教授
宋杰
来源:  发布时间:2017-03-06 

职称:  特别研究员、博导
研究方向:医疗仪器及智能诊断;

                 高分辨成像及单细胞操纵;

                 DNA纳米技术及其在生物医学上的应用
办公室:微纳综合实验楼1-512
办公电话:34207437

电子邮箱:sjie@sjtu.edu.cn
                                      招生情况:欢迎有研究兴趣的本科生加入实验室参与课题研究;

                                                         招收具有物理、化学、生物、材料以及医学相关的研究生和博士生以及博士后;

个人简介


        宋杰,特别研究员,博士生导师。于2009年兰州大学物理专业本科毕业,2014年获得丹麦奥胡斯大学生物物理方向博士学位。之后在丹麦奥胡斯大学和美国埃默里大学从事为期两年的博士后研究。前期主要致力于环境可控多功能新型扫描探针显微镜的开发,进而结合低温冷冻电子显微镜,研究水分子表面自组装热动力学,探索DNA自组装纳米结构及其热动力学机理,以及解析致病多肽以及细菌纤维生物组织结构与功能,同时亦应用于其他相关涵盖物理,化学,生物,医学等多个交叉学科领域, 近五年来在Science, Nature, Nature Chemistry, Nature Nanotechnology, Nature Communication等国际知名杂志发表论文30多篇,其中第一作者与通讯作者论文14篇,他引1000多次,H因子 18 。

 

 

研究方向 


      现在作为课题组负责人,将主要集中在以下三个方面的研究:
     1、功能纳米材料及其在生物医学工程 上的应用
     2、高分辨动态成像及生物小分子结构功能分析;
     3、DNA纳米技术及其相关应用
     4、单细胞操纵,以及单细胞基因、单细胞酶学分析

 

 

 

代表性学术论文(*同等贡献;#通讯作者)


      1.   Jie Song*#, Z. Li*, P. Wang*, T. Meyer, C.D. Mao#, Y. Ke#: Reconfiguration of DNA Molecular Arrays Driven by Information Relay, Science 2017 (In press)
       2.  Y.X. Pan, J.B. Peng, S. Xin, Y. You, Y.L. Men, F. Zhang, M.Y. Duan, Y. Cui, Z.Q. Sun and Jie Song#, Enhanced Visible-Light-Driven Photocatalytic H2 Evolution from Water on Noble-Metal-Free CdS-Nanoparticle-Dispersed Mo2C@C Nanospheres, ACS Sustainable Chem. Eng., 2017 5(6), 5449
     3.  Q. Zhang, T. Yin, G. Gao, J. G. Shapter, W. Lai, P. Huang, W. Qi, Jie Song, and D.X. Cui: Multifunctional Core@Shell Magnetic Nanoprobes for Enhancing Targeted Magnetic Resonance Imaging and Fluorescent Labeling in Vitro and in Vivo, ACS Appl. Mater. Interfaces, 2017, 9 (21), pp 17777–17785
     4.  Y. Ma, H.L. Fu, Z, Wang, H. Huang, J. Ni, Jie Song, Y. Xia, W.L. Xia, W.L. Jin, D.X. Cui: USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein, Oncotarget, 2017 (8) 33329
     5.  C.X. Yue, Y.M Yang, C.L. Zhang, G. Alfranca, S. Cheng, L. Ma, Y. Liu, X. Zhi, J. Ni, W. Jiang, Jie Song, J.M. Fuente and D.X. Cui: ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source, Theranostics 2016 6(13) 2352
     6.  Qinghui Zeng, Q Li, W Ji, X Bin, Jie Song# :Highly Sensitive Homogeneous Immunoassays Based on Construction of Silver Triangular Nanoplates-Quantum Dots FRET System,  Scientific reports, 2016, 6, 26534
     7.   YX Pan, ZQ Sun, HP Cong, YL Men, S Xin, Jie Song#, SH Yu#: Photocatalytic CO2 reduction highly enhanced by oxygen vacancies on Pt-nanoparticle-dispersed gallium oxide, Nano Research, 2016 1-12  

 

Before SJTU
      1.  Jakob Bach Knudsen, Lei Liu, Anne Louise Bank Kodal, Mikael Madsen, Qiang Li, Jie Song, Johannes B Woehrstein, Shelley FJ Wickham, Maximilian T Strauss, Florian Schueder, Jesper Vinther, Abhichart Krissanaprasit, Daniel Gudnason, Anton Allen Abbotsford Smith, Ryosuke Ogaki, Alexander N Zelikin, Flemming Besenbacher, Victoria Birkedal, Peng Yin, William M Shih, Ralf Jungmann, Mingdong Dong, Kurt V Gothelf: Routing of individual polymers in designed patterns. Nature Nanotechnology, 2015, 10, 892
     2.  Qiang Li, Jie Song, Flemming Besenbacher, Mingdong Dong: Two-dimensional material confined water, Accounts of chemical research, 2014, 48, 119
    3.  Q. Zeng, Y. Zhang, D. Shao, W. Ji, X Kong, J. Li, L. Chen and Jie Song#, Straightforward strategy of surface chemistry on gold nanoparticles via silica encapsulating for human hepatocarcinoma cell application. ACS Applied Materials & Interfaces, 2014, 6, 19327
      4.  Jie Song✳, Qiang Li✳, Jørgen Kjems, Flemming Besenbacher, and Mingdong Dong: Evidence of Stranski-Krastanov Growth at the Initial Stage of Atmospheric Water Condensation, Nature Communications, 2014, 5, 4837
      5.  Qinghui Zeng, Dan Shao, Wenyu Ji, Jing Li, Li Chen and Jie Song#: The nanotoxicity investigation of optical nanoparticles to cultured cells in vitro. Toxicology Reports 2014, 1, 137
     6.  Y. Ke, L. L.Ong, W. Sun, Jie Song, Mingdong Dong, William M.Shih, P. Yin : Complex Crystals with Prescribed Depth, Nature C hemistry, 2014, 6, 994
     7.  Zhao Zhang✳, Jie Song✳,Flemming Besenbacher, Mingdong Dong, Kurt V. Gothelf, Self-Assembly of DNA Origami and Single- Stranded Tile Structures at Room Temperature, Angewandte Chemie 2013, 125, 9389 
     8.  Jie Song, Zhao Zhang, Shuai Zhang, Lei Liu, Qiang Li, Erqing Xie, Kurt Vesterager Gothelf, Flemming Besenbacher, Mingdong Dong: Isothermal Hybridization Kinetics of DNA Assembly of Two-Dimensional DNA Origami. Small, 2013, 9, 2954-2959.
     9.  Zhang S.; Andreasen, M.; Nielsen, J.T.; Nielsen, E.H.; Liu, L.; Jie Song; Ji, G.; Sun, F.; Skrydstrup, T.; Nielsen N.C.; Besenbacher, F.; Otzen, D.E.; Dong, M: Coexistence of ribbon and helical fibrils originating from hIAPP20-29 revealed by quantitative nanomechanical atomic force microscopy. PNAS, 2013, 110(8):2798-803
    10.  Christian Pfeffer, Steffen Larsen, Jie Song, Mingdong Dong, Flemming Besenbacher, Rikke Meyer, Kasper Urup Kjeldsen, Lars Schreiber, Yuri Gorby, Mohamed El-Naggar, Kar Man Leung, Andreas Schramm, Nils Risgaard-Petersen  and Lars Peter Nielsen: Filamentous bacteria transport electrons over centimetres distances, Nature, 2012 491, 218–221
    11.  Jie Song, Jean-Michel Arbona, Zhao Zhang, Lei Liu, Erqing Xie, Juan Elezgaray, Jean-Pierre Aime, Kurt Vesterager Gothelf, Flemming Besenbacher, Mingdong Dong: Direct Visualization of Transient Thermal Response of a DNA Origami, J. Am. Chem. Soc, 2012, 134, 984
     12.  Jie Song, Derya Kahveci, Menglin Chen, Zhen Guo, Erqing Xie, Xuebin Xu,  Flemming Besenbacher, Mingdong Dong: Enhanced Catalytic Activity of Lipase Encapsulated in PCL Nanofibers, Langmuir, 2012, 28 (14), pp 6157–6162
     13.  Jie Song, Menglin Chen, Viduthalai R. Regina, Chenxuan Wang, Rikke L. Meyer, Erqing Xie, Chen Wang, Flemming Besenbacher and Mingdong Dong: Safe and Effective Ag Nanoparticles immobilized Antimicrobial NanoNonwovens. Advanced biomaterials. 2012, 5, B24
     14.  Jie Song, Menglin Chen, Mikkel Buster Olesen, Chenxuan Wang, Rasmus Havelund, Qiang Li, Erqing Xie, Rong Yang, Peter Bøggild, Chen Wang, Flemming Besenbacher and Mingdong Dong: Direct electrospinning ofAg/polyvinylpyrrolidone nanocables. Nanoscale, 2011, 3, 4966
    15.  Jie Song, Xiuyun An, Jinyuan Zhou, Yanxia Liu, Wei Wang, Xiaodong Li, Wei Lan, Erqing Xie: Investigation of enhanced ultraviolet emission from different Ti-capped ZnO structures via surface passivation and surface plasmon coupling. Appl. Phys. Lett. 2010, 97(12), 122103
    16.  Jie Song, Jinyuan Zhou, Wei Wang, Yanxia Liu, Xiaodong Li, Xianbo Xu, Erqing Xie: Growth mechanism and photoluminescent properties of AlN/ZnO heterostructures. J. Phys. Chem. C 2010, 114(24), 10761.
 

 

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